Inhaled hypertonic saline in adults hospitalised for exacerbation of cystic fibrosis lung disease: a retrospective study.

ABSTRACT:

Background

Inhaled hypertonic saline (HTS) improves quality of life and reduces pulmonary exacerbations when given long term in patients with cystic fibrosis (CF). While increasingly being offered for acute pulmonary exacerbations, little is known about the efficacy in this setting.

Objectives

The authors examined the tolerability and efficacy of HTS use among adult subjects hospitalised with a CF pulmonary exacerbation and hypothesised that use of HTS would improve pulmonary function during the admission.

Design

Pilot retrospective non-randomised study.

Setting

Single tertiary care centre.

Participants

45 subjects admitted to the inpatient service for acute CF pulmonary exacerbation in 2006-2007. A subset of 18 subjects who were also admitted in 2005 wh

SUBMITTER: Pezzulo AA 

PROVIDER: S-EPMC3332252 | biostudies-literature | 2012

REPOSITORIES: biostudies-literature