Propofol vs midazolam plus fentanyl for upper gastrointestinal endomicroscopy: a randomized trial.

ABSTRACT:

Aim

To compare the endomicroscopic image quality of integrated confocal laser endomicroscopy (iCLE) and sedation efficacy of propofol vs midazolam plus fentanyl (M/F).

Methods

Consecutive outpatients undergoing iCLE were prospectively recruited and randomized to the propofol group (P group) or M/F group. The patient, performing endoscopist and endoscopic assistant were blinded to the randomization. The quality of endomicroscopic images and anesthetic efficacy outcomes were blindly evaluated after iCLE examination.

Results

There were significantly more good quality endomicroscopic images in the propofol group than in the M/F group (72.75% vs 52.89%, P < 0.001). The diagnostic accuracy for upper gastrointestinal mucosal lesions using confocal laser endomicroscopy favors

SUBMITTER: Zuo XL 

PROVIDER: S-EPMC3332296 | biostudies-literature | 2012 Apr

REPOSITORIES: biostudies-literature