Dose-responses from multi-model inference for the non-cancer disease mortality of atomic bomb survivors.

ABSTRACT: The non-cancer mortality data for cerebrovascular disease (CVD) and cardiovascular diseases from Report 13 on the atomic bomb survivors published by the Radiation Effects Research Foundation were analysed to investigate the dose-response for the influence of radiation on these detrimental health effects. Various parametric and categorical models (such as linear-no-threshold (LNT) and a number of threshold and step models) were analysed with a statistical selection protocol that rated the model description of the data. Instead of applying the usual approach of identifying one preferred model for each data set, a set of plausible models was applied, and a sub-set of non-nested models was identified that all fitted the data about equally well. Subsequently, this sub-set of non-nested models w

SUBMITTER: Schollnberger H 

PROVIDER: S-EPMC3332375 | biostudies-literature | 2012 May

REPOSITORIES: biostudies-literature