Beyond the broken error-related negativity: functional and diagnostic correlates of error processing in psychosis.

ABSTRACT:

Background

Studies of event-related potentials have consistently shown that schizophrenia is associated with a blunted error-related negativity (ERN), indicating a deficit in error monitoring. It is unknown whether this deficit is unique to schizophrenia or is common to psychotic disorders more broadly, and its associations with clinical characteristics of the illness are not well understood.

Methods

The ERN and the error positivity (Pe) were recorded from 33 individuals with schizophrenia, 45 individuals with other psychotic disorders, and 33 healthy control subjects. Patients were drawn from a cohort with psychotic disorders followed since first hospitalization and diagnosed by consensus based on 10 years of observation.

Results

The ERN was profoundly blunted in the

SUBMITTER: Foti D 

PROVIDER: S-EPMC3334442 | biostudies-literature | 2012 May

REPOSITORIES: biostudies-literature