Indocyanine green fluorescence imaging for evaluation of uterine blood flow in cynomolgus macaque.

ABSTRACT:

Background

Uterine blood flow is an important factor in uterine viability, but the number of blood vessels required to maintain viability is uncertain. In this study, indocyanine green (ICG) fluorescence imaging was used to examine uterine hemodynamics and vessels associated with uterine blood flow in cynomolgus macaque.

Methods

The uterus of a female cynomolgus macaque was cut from the vaginal canal to mimic a situation during trachelectomy or uterine transplantation surgery in which uterine perfusion is maintained only with uterine and ovarian vessels. Intraoperative uterine hemodynamics was observed using ICG fluorescence imaging under conditions in which various nutrient vessels were selected by clamping of blood vessels. A time-intensity curve was plotted using imaging

SUBMITTER: Kisu I 

PROVIDER: S-EPMC3335048 | biostudies-literature | 2012

REPOSITORIES: biostudies-literature