Developing a nanoparticle test for prostate cancer scoring.

ABSTRACT:

Background

Over-diagnosis and treatment of prostate cancer has been a major problem in prostate cancer care and management. Currently the most relevant prognostic factor to predict a patient's risk of death due to prostate cancer is the Gleason score of the biopsied tissue samples. However, pathological analysis is subjective, and the Gleason score is only a qualitative estimate of the cancer malignancy. Molecular biomarkers and diagnostic tests that can accurately predict prostate tumor aggressiveness are rather limited.

Method

We report here for the first time the development of a nanoparticle test that not only can distinguish prostate cancer from normal and benign conditions, but also has the potential to predict the aggressiveness of prostate cancer quantitatively. To c

SUBMITTER: Huo Q 

PROVIDER: S-EPMC3337274 | biostudies-literature | 2012 Mar

REPOSITORIES: biostudies-literature