Impaired survival and long-term neurological problems in benign meningioma.

ABSTRACT:

Purpose

To assess long-term functional outcome and survival among patients with meningioma World Health Organization (WHO) grade I.

Methods

Retrospective analysis of 205 patients after resection of WHO grade I intracranial meningioma from 1985 through 2003. Expected age- and sex-specific survival was calculated by applying Dutch life-table statistics to each patient for the individual duration of follow-up. Long-term functional outcome was assessed using a mailed questionnaire to the general practitioner.

Results

The mean duration of follow-up was 11.5 years. Survival at 5, 10, 15, and 20 years was 92%, 81%, 63%, and 53%, respectively, which is significantly lower than the expected survival (94%, 86%, 78%, and 66%, respectively). Survival was worse with higher age (P

SUBMITTER: van Alkemade H 

PROVIDER: S-EPMC3337301 | biostudies-literature | 2012 May

REPOSITORIES: biostudies-literature