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Emv2, the only endogenous ecotropic murine leukemia virus of C57BL/6J mice.


ABSTRACT: With the proliferation of sequence data, great challenges are posed in the correct annotation of endogenous retroviruses, which together comprise up to ten per cent of the genomes of many organisms. It is therefore essential that all sources of information are carefully considered before drawing conclusions concerning the phylogeny, distribution and biological properties of endogenous retroviruses. We suggest that such due diligence has not been applied in the description of an endogenous ecotropic retrovirus that recently appeared in Retrovirology.

SUBMITTER: Young GR 

PROVIDER: S-EPMC3337817 | biostudies-literature | 2012 Mar

REPOSITORIES: biostudies-literature

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Emv2, the only endogenous ecotropic murine leukemia virus of C57BL/6J mice.

Young George R GR   Kassiotis George G   Stoye Jonathan P JP  

Retrovirology 20120322


With the proliferation of sequence data, great challenges are posed in the correct annotation of endogenous retroviruses, which together comprise up to ten per cent of the genomes of many organisms. It is therefore essential that all sources of information are carefully considered before drawing conclusions concerning the phylogeny, distribution and biological properties of endogenous retroviruses. We suggest that such due diligence has not been applied in the description of an endogenous ecotro  ...[more]

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