Comorbidity and sex-related differences in mortality in oxygen-dependent chronic obstructive pulmonary disease.

ABSTRACT:

Background

It is not known why survival differs between men and women in oxygen-dependent chronic obstructive pulmonary disease (COPD). The present study evaluates differences in comorbidity between men and women, and tests the hypothesis that comorbidity contributes to sex-related differences in mortality in oxygen-dependent COPD.

Methods

National prospective study of patients aged 50 years or older, starting long-term oxygen therapy (LTOT) for COPD in Sweden between 1992 and 2008. Comorbidities were obtained from the Swedish Hospital Discharge Register. Sex-related differences in comorbidity were estimated using logistic regression, adjusting for age, smoking status and year of inclusion. The effect of comorbidity on overall mortality and the interaction between comorbidit

SUBMITTER: Ekstrom MP 

PROVIDER: S-EPMC3338527 | biostudies-literature | 2012

REPOSITORIES: biostudies-literature