MycoRRdb: a database of computationally identified regulatory regions within intergenic sequences in mycobacterial genomes.

ABSTRACT: The identification of regulatory regions for a gene is an important step towards deciphering the gene regulation. Regulatory regions tend to be conserved under evolution that facilitates the application of comparative genomics to identify such regions. The present study is an attempt to make use of this attribute to identify regulatory regions in the Mycobacterium species followed by the development of a database, MycoRRdb. It consist the regulatory regions identified within the intergenic distances of 25 mycobacterial species. MycoRRdb allows to retrieve the identified intergenic regulatory elements in the mycobacterial genomes. In addition to the predicted motifs, it also allows user to retrieve the Reciprocal Best BLAST Hits across the mycobacterial genomes. It is a useful resource to u

SUBMITTER: Midha M 

PROVIDER: S-EPMC3338573 | biostudies-literature | 2012

REPOSITORIES: biostudies-literature