Vitamin C and asthma in children: modification of the effect by age, exposure to dampness and the severity of asthma.

ABSTRACT:

Background

We previously found a significant benefit of vitamin C supplementation in asthmatic children.

Purpose

To test whether the effect of vitamin C on asthma is heterogeneous over the participant population.

Methods

Egyptian asthmatic children between 7 and 10 years of age (n = 60) were included in the cross-over trial. They were administered 0.2 grams per day of vitamin C and placebo for separate 6-week periods. The variation in the vitamin C effect on two clinically relevant outcomes was analyzed: the childhood asthma control test (C-ACT), which measures the severity of asthma symptoms (the scale ranges from 0 to 27 points, < 20 points indicating unsatisfactory asthma control), and FEV1. We used linear modeling to examine the variation of the vitamin C effect i

SUBMITTER: Hemila H 

PROVIDER: S-EPMC3339402 | biostudies-literature | 2011 Aug

REPOSITORIES: biostudies-literature