Sex-specific selection for MHC variability in Alpine chamois.

ABSTRACT:

Background

In mammals, males typically have shorter lives than females. This difference is thought to be due to behavioural traits which enhance competitive abilities, and hence male reproductive success, but impair survival. Furthermore, in many species males usually show higher parasite burden than females. Consequently, the intensity of selection for genetic factors which reduce susceptibility to pathogens may differ between sexes. High variability at the major histocompatibility complex (MHC) genes is believed to be advantageous for detecting and combating the range of infectious agents present in the environment. Increased heterozygosity at these immune genes is expected to be important for individual longevity. However, whether males in natural populations benefit more from M

SUBMITTER: Schaschl H 

PROVIDER: S-EPMC3340304 | biostudies-literature | 2012 Feb

REPOSITORIES: biostudies-literature