An exploratory analysis of γ-synuclein expression in endometrioid endometrial cancer.

ABSTRACT:

Objective

This study aims to investigate the expression of γ-synuclein in endometrioid endometrial carcinoma and assess if the γ-synuclein expression correlates with the aggression of the tumour and its prognostic value in endometrioid endometrial carcinoma.

Design

This retrospective study evaluated (60) specimens of the primary untreated endometrioid endometrial carcinoma and (12) normal endometrium tissues, and the expression of γ-synuclein was checked by immunohistochemistry. The correlation between γ-synuclein expression and the clinicopathological features of patients with endometrioid endometrial carcinoma was analysed, and SPSS V.13.0 software was used for statistical analysis.

Results

The expression of γ-synuclein was positive in 48.3% (29/60) endometrioid end

SUBMITTER: Zou J 

PROVIDER: S-EPMC3341596 | biostudies-literature | 2012

REPOSITORIES: biostudies-literature