Relationship between bitter-taste receptor genotype and solid medication formulation usage among young children: a retrospective analysis.

ABSTRACT:

Background

Children often refuse to take medication in liquid formulation because of its unpleasant taste. Recent advances in taste genetics have provided some insight into individual differences in taste among children: due to their genotype, some prefer more intense sweetness and are more sensitive to bitter tastes and thus may have different needs for medication formulation.

Objective

The aims of this study were to: (1) test the a priori hypothesis that children with the bitter-sensitive genotypes are more likely to have experienced solid medication formulations than those with the bitter-insensitive genotype; and (2) conduct post hoc analyses to examine the relationship between genotype and most preferred level of sucrose in water because sweeteners are a common componen

SUBMITTER: Lipchock SV 

PROVIDER: S-EPMC3341939 | biostudies-literature | 2012 Mar

REPOSITORIES: biostudies-literature