The genome of Ganoderma lucidum provides insights into triterpenes biosynthesis and wood degradation [corrected].

ABSTRACT:

Background

Ganoderma lucidum (Reishi or Ling Zhi) is one of the most famous Traditional Chinese Medicines and has been widely used in the treatment of various human diseases in Asia countries. It is also a fungus with strong wood degradation ability with potential in bioenergy production. However, genes, pathways and mechanisms of these functions are still unknown.

Methodology/principal findings

The genome of G. lucidum was sequenced and assembled into a 39.9 megabases (Mb) draft genome, which encoded 12,080 protein-coding genes and ∼83% of them were similar to public sequences. We performed comprehensive annotation for G. lucidum genes and made comparisons with genes in other fungi genomes. Genes in the biosynthesis of the main G. lucidum active ingredients, ganoderic acids

SUBMITTER: Liu D 

PROVIDER: S-EPMC3342255 | biostudies-literature | 2012

REPOSITORIES: biostudies-literature