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6β-Methyl-3,20-dioxopregn-4-en-17-yl acetate.

ABSTRACT: The title compound, C(24)H(34)O(4), is a precursor of Megestrol acetate. Ring A has a half-chair conformation [Q = 0.446 (3) Å, θ = 54.6 (4)° and ϕ = 9.5 (4)°]. Ring D adopts a 13β-envelope conformation [Q = 0.463 (2) Å and ϕ = 188.2 (3)°].

SUBMITTER: Chen L

PROVIDER: S-EPMC3343965 | biostudies-literature | 2012 Apr

REPOSITORIES: biostudies-literature

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6β-Methyl-3,20-dioxopregn-4-en-17-yl acetate.

Chen Longran L Liu Xuefen X Yang Peng P

Acta crystallographica. Section E, Structure reports online 20120310 Pt 4

The title compound, C(24)H(34)O(4), is a precursor of Megestrol acetate. Ring A has a half-chair conformation [Q = 0.446 (3) Å, θ = 54.6 (4)° and ϕ = 9.5 (4)°]. Ring D adopts a 13β-envelope conformation [Q = 0.463 (2) Å and ϕ = 188.2 (3)°]. ...[more]

PMID: 22590046

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