Lithium cation enhances anion binding in a tripodal phosphine oxide-based ditopic receptor.

ABSTRACT: A tripodal ditopic receptor presents H-bond donors and a phosphine oxide to potential guests. In the idealized binding conformation, an endohedral P=O functionality provides enhanced halide binding in the presence of lithium with the greatest ΔΔG° observed for bromide, while minimal changes in K(a) are observed in the presence of sodium.

SUBMITTER: Gavette JV 

PROVIDER: S-EPMC3344749 | biostudies-literature | 2011 Jul

REPOSITORIES: biostudies-literature