Repeatability of in vivo parafoveal cone density and spacing measurements.

ABSTRACT:

Purpose

To assess the repeatability and measurement error associated with cone density and nearest neighbor distance (NND) estimates in images of the parafoveal cone mosaic obtained with an adaptive optics scanning light ophthalmoscope (AOSLO).

Methods

Twenty-one participants with no known ocular pathology were recruited. Four retinal locations, approximately 0.65° eccentricity from the center of fixation, were imaged 10 times in randomized order with an AOSLO. Cone coordinates in each image were identified using an automated algorithm (with or without manual correction) from which cone density and NND were calculated. Owing to naturally occurring fixational instability, the 10 images recorded from a given location did not overlap entirely. We thus analyzed each image set bo

SUBMITTER: Garrioch R 

PROVIDER: S-EPMC3348369 | biostudies-literature | 2012 May

REPOSITORIES: biostudies-literature