Allelic expression changes in Medaka (Oryzias latipes) hybrids between inbred strains derived from genetically distant populations.

ABSTRACT: Variations in allele expressions between genetically distant populations are one of the most important factors which affects their morphological and physiological variations. These variations are caused by natural mutations accumulated in their habitats. It has been reported that allelic expression differences in the hybrids of genetically distant populations are different from parental strains. In that case, there is a possibility that allelic expression changes lead to novel phenotypes in hybrids. Based on genomic information of the genetically distant populations, quantification and comparison of allelic expression changes make importance of regulatory sequences (cis-acting factors) or upstream regulatory factors (trans-acting modulators) for these changes clearer. In this study, we foc

SUBMITTER: Murata Y 

PROVIDER: S-EPMC3349633 | biostudies-literature | 2012

REPOSITORIES: biostudies-literature