In-line filtration reduces severe complications and length of stay on pediatric intensive care unit: a prospective, randomized, controlled trial.

ABSTRACT:

Purpose

Particulate contamination due to infusion therapy carries a potential health risk for intensive care patients.

Methods

This single-centre, prospective, randomized controlled trial assessed the effects of filtration of intravenous fluids on the reduction of complications in critically ill children admitted to a pediatric intensive care unit (PICU). A total of 807 subjects were randomly assigned to either a control (n = 406) or filter group (n = 401), with the latter receiving in-line filtration. The primary endpoint was reduction in the rate of overall complications, which included the occurrence of systemic inflammatory response syndrome (SIRS), sepsis, organ failure (circulation, lung, liver, kidney) and thrombosis. Secondary objectives were a reduction in the lengt

SUBMITTER: Jack T 

PROVIDER: S-EPMC3351606 | biostudies-literature | 2012 Jun

REPOSITORIES: biostudies-literature