Safety of prior endoscopic mucosal resection in patients receiving radiofrequency ablation of Barrett's esophagus.

ABSTRACT:

Background & aims

Radiofrequency ablation (RFA) is safe and effective treatment for flat dysplasia associated with Barrett's esophagus (BE). However, there are limited data on the safety of RFA in patients who had prior endoscopic mucosal resection (EMR), which might increase the risk of complications. We compared complications and histologic outcomes between patients who had EMR before RFA and those who received only RFA.

Methods

We performed a retrospective analysis of data collected from patients treated for BE, associated with dysplasia or intramucosal cancer, at the Mayo Clinic in Rochester, Minnesota, from 1998-2009. Patients were divided into groups that had RFA after EMR (group 1, n = 44) or only RFA (group 2, n = 46). We compared the incidence of complications (stri

SUBMITTER: Okoro NI 

PROVIDER: S-EPMC3351797 | biostudies-literature | 2012 Feb

REPOSITORIES: biostudies-literature