Exploring the origin and degree of genetic isolation of Anopheles gambiae from the islands of Sao Tome and Principe, potential sites for testing transgenic-based vector control.

ABSTRACT: The evolutionary processes at play between island and mainland populations of the malaria mosquito vector Anopheles gambiae sensu stricto are of great interest as islands may be suitable sites for preliminary application of transgenic-based vector control strategies. São Tomé and Príncipe, located off the West African coast, have received such attention in recent years. This study investigates the degree of isolation of An. gambiae s.s. populations between these islands and the mainland based on mitochondrial and ribosomal DNA molecular data. We identify possible continental localities from which these island populations derived. For these purposes, we used F ST values, haplotype networks, and nested clade analysis to estimate migration rates and patterns. Haplotypes from both markers are

SUBMITTER: Marshall JC 

PROVIDER: S-EPMC3352388 | biostudies-literature | 2008 Nov

REPOSITORIES: biostudies-literature