Endemic pemphigus over a century: Part II.

ABSTRACT:

Background

Endemic pemphigus foliaceus (EPF) is an autoimmune disease, classically occurring in a restricted geographic area. Foci of EPF have been described in several Central and South American countries, often affecting young people and Amerindians, with some female predilection. Although most American EPF cases have been documented in Brazil, cases have been reported in Peru, Paraguay, El Salvador and Venezuela. An additional variant of EPF has been described in El Bagre, Colombia, (El Bagre-EPF) affecting older men and a few post-menopausal females. Finally, one additional type of EPF has been described in nomadic tribes affecting females of child bearing age in Tunisia, Africa.

Aims

The main aim of this review is to summarize current knowledge about autoantigens, and i

SUBMITTER: Abreu-Velez AM 

PROVIDER: S-EPMC3354423 | biostudies-literature | 2010 Mar

REPOSITORIES: biostudies-literature