The effect of vertical sleeve gastrectomy on food choice in rats.

ABSTRACT:

Objective

Diets high in fat are implicated in the development and maintenance of obesity, and obese individuals display greater preferences for high-fat foods than do their lean counterparts. Weight-reduction bariatric surgery is associated with changes in food choice. In particular, after Roux-en-Y gastric bypass (RYGB), humans and rodents select or prefer foods that are lower in fat content. We asked whether a bariatric surgical procedure limited to the stomach, vertical sleeve gastrectomy (VSG), causes a similar reduction of fat intake/preference.

Research design and methods

Rats received VSG or Sham surgery or remained surgically naïve, and were assessed for food preference using three diet-choice paradigms. Using progressive-ratio (PR) and conditioned taste aversion par

SUBMITTER: Wilson-Perez HE 

PROVIDER: S-EPMC3355245 | biostudies-literature | 2013 Feb

REPOSITORIES: biostudies-literature