ArrayMap: a reference resource for genomic copy number imbalances in human malignancies.

ABSTRACT:

Background

The delineation of genomic copy number abnormalities (CNAs) from cancer samples has been instrumental for identification of tumor suppressor genes and oncogenes and proven useful for clinical marker detection. An increasing number of projects have mapped CNAs using high-resolution microarray based techniques. So far, no single resource does provide a global collection of readily accessible oncogenomic array data.

Methodology/principal findings

We here present arrayMap, a curated reference database and bioinformatics resource targeting copy number profiling data in human cancer. The arrayMap database provides a platform for meta-analysis and systems level data integration of high-resolution oncogenomic CNA data. To date, the resource incorporates more than 40,000 a

SUBMITTER: Cai H 

PROVIDER: S-EPMC3356349 | biostudies-literature | 2012

REPOSITORIES: biostudies-literature