Effects of fatty acid treatments on the dexamethasone-induced intramuscular lipid accumulation in chickens.

ABSTRACT:

Background

Glucocorticoid has an important effect on lipid metabolism in muscles, and the type of fatty acid likely affects mitochondrial utilization. Therefore, we hypothesize that the different fatty acid types treatment may affect the glucocorticoid induction of intramuscular lipid accumulation.

Methodology/principal findings

The effect of dexamethasone (DEX) on fatty acid metabolism and storage in skeletal muscle of broiler chickens (Gallus gallus domesticus) was investigated with and without fatty acid treatments. Male Arbor Acres chickens (31 d old) were treated with either palmitic acid (PA) or oleic acid (OA) for 7 days, followed by DEX administration for 3 days (35-37 d old). The DEX-induced lipid uptake and oxidation imbalance, which was estimated by increased fatt

SUBMITTER: Wang Xj 

PROVIDER: S-EPMC3356436 | biostudies-literature | 2012

REPOSITORIES: biostudies-literature