Association between calcifying nanoparticles and placental calcification.

ABSTRACT:

Background

The purpose of this study was to examine the possible contribution of calcifying nanoparticles to the pathogenesis of placental calcification.

Methods

Calcified placental tissues and distal tissue samples were collected from 36 confirmed placental calcification cases. In addition, 20 normal placental tissue samples were obtained as a control group. All the tissue samples were cultured using special nanobacterial culture methods. The cultured calcifying nanoparticles were examined by transmission electron microscopy (TEM), and their growth was monitored by optical density (OD) at a wavelength of 650 nm. 16S rRNA gene expression of the cultured calcifying nanoparticles was also isolated and sequenced.

Results

Novel calcifying nanoparticles wrapped with electr

SUBMITTER: Guo Y 

PROVIDER: S-EPMC3357051 | biostudies-literature | 2012

REPOSITORIES: biostudies-literature