Associations of triiodothyronine levels with carotid atherosclerosis and arterial stiffness in hemodialysis patients.

ABSTRACT:

Background and objectives

End-stage renal disease is linked to alterations in thyroid hormone levels and/or metabolism, resulting in a high prevalence of subclinical hypothyroidism and low triiodothyronine (T3) levels. These alterations are involved in endothelial damage, cardiac abnormalities, and inflammation, but the exact mechanisms are unclear. In this study, we investigated the relationship between serum free-T3 (fT3) and carotid artery atherosclerosis, arterial stiffness, and vascular calcification in prevalent patients on conventional hemodialysis.

Design, setting, participants, & measurements

137 patients were included. Thyroid-hormone levels were determined by chemiluminescent immunoassay, carotid artery-intima media thickness (CA-IMT) by Doppler ultrasonography, c

SUBMITTER: Tatar E 

PROVIDER: S-EPMC3358995 | biostudies-literature | 2011 Sep

REPOSITORIES: biostudies-literature