Measuring Granger causality between cortical regions from voxelwise fMRI BOLD signals with LASSO.

ABSTRACT: Functional brain network studies using the Blood Oxygen-Level Dependent (BOLD) signal from functional Magnetic Resonance Imaging (fMRI) are becoming increasingly prevalent in research on the neural basis of human cognition. An important problem in functional brain network analysis is to understand directed functional interactions between brain regions during cognitive performance. This problem has important implications for understanding top-down influences from frontal and parietal control regions to visual occipital cortex in visuospatial attention, the goal motivating the present study. A common approach to measuring directed functional interactions between two brain regions is to first create nodal signals by averaging the BOLD signals of all the voxels in each region, and to then meas

SUBMITTER: Tang W 

PROVIDER: S-EPMC3359965 | biostudies-literature | 2012

REPOSITORIES: biostudies-literature