Preventing cognitive decline in older African Americans with mild cognitive impairment: design and methods of a randomized clinical trial.

ABSTRACT: Mild Cognitive Impairment (MCI) affects 25% of older African Americans and predicts progression to Alzheimer's disease. An extensive epidemiologic literature suggests that cognitive, physical, and/or social activities may prevent cognitive decline. We describe the methods of a randomized clinical trial to test the efficacy of Behavior Activation to prevent cognitive decline in older African Americans with the amnestic multiple domain subtype of MCI. Community Health Workers deliver 6 initial in-home treatment sessions over 2-3 months and then 6 subsequent in-home booster sessions using language, materials, and concepts that are culturally relevant to older African Americans during this 24 month clinical trial. We are randomizing 200 subjects who are recruited from churches, senior centers,

SUBMITTER: Rovner BW 

PROVIDER: S-EPMC3361551 | biostudies-literature | 2012 Jul

REPOSITORIES: biostudies-literature