An fMRI study of attentional control in the context of emotional distracters in euthymic adults with bipolar disorder.

ABSTRACT: Inability to modulate attention away from emotional stimuli may be a key component of dysregulated emotion in bipolar disorder (BD). Previous studies of BD indicate abnormalities in neural circuitry underlying attentional control, yet few studies examined attentional control in the context of emotional distracters. We compared activity and connectivity in neural circuitry supporting attentional control and emotion processing among 22 individuals with BD type 1, currently remitted and euthymic, and 19 healthy controls. Participants performed an emotional n-back paradigm, comprising high and low attentional demand conditions, each with either emotional (happy, fearful), neutral or no face flanker distracters. During the high attentional control demand conditions without emotional distracters

SUBMITTER: Mullin BC 

PROVIDER: S-EPMC3361638 | biostudies-literature | 2012 Mar

REPOSITORIES: biostudies-literature