Alternative sigma factor σH activates competence gene expression in Lactobacillus sakei.

ABSTRACT:

Background

Alternative sigma factors trigger various adaptive responses. Lactobacillus sakei, a non-sporulating meat-borne bacterium, carries an alternative sigma factor seemingly orthologous to σ(H) of Bacillus subtilis, best known for its contribution to the initiation of a large starvation response ultimately leading to sporulation. As the role of σ(H)-like factors has been little studied in non-sporulating bacteria, we investigated the function of σ(H) in L. sakei.

Results

Transcription of sigH coding for σ(H) was hardly affected by entry into stationary phase in our laboratory conditions. Twenty-five genes potentially regulated by σ(H) in L. sakei 23 K were revealed by genome-wide transcriptomic profiling of sigH overexpression and/or quantitative PCR analysis. More tha

SUBMITTER: Schmid S 

PROVIDER: S-EPMC3364868 | biostudies-literature | 2012 Mar

REPOSITORIES: biostudies-literature