Parenteral fish oil as monotherapy prevents essential fatty acid deficiency in parenteral nutrition-dependent patients.

ABSTRACT:

Objective

The use of fish oil-based emulsions as the sole source of fat for patients receiving parenteral nutrition (PN) has raised concerns for the development of essential fatty acid deficiency (EFAD), hindering its adoption into clinical practice. The purpose of the present study was to examine fatty acid profiles of patients receiving no enteral energy, while completely dependent on PN and an intravenous fish oil-based lipid emulsion, for onset of EFAD and maintenance of growth.

Patients and methods

Prospectively collected data from 10 patients were reviewed for evidence of EFAD, defined as a triene:tetraene ratio >0.2. Gestational age-adjusted z scores for length, growth, and head circumference at baseline were compared with the corresponding z scores at time of censori

SUBMITTER: de Meijer VE 

PROVIDER: S-EPMC3365554 | biostudies-literature | 2010 Feb

REPOSITORIES: biostudies-literature