An automated database case definition for serious bleeding related to oral anticoagulant use.

ABSTRACT:

Purpose

Bleeding complications are a serious adverse effect of medications that prevent abnormal blood clotting. To facilitate epidemiologic investigations of bleeding complications, we developed and validated an automated database case definition for bleeding-related hospitalizations.

Methods

The case definition utilized information from an in-progress retrospective cohort study of warfarin-related bleeding in Tennessee Medicaid enrollees 30 years of age or older. It identified inpatient stays during the study period of January 1990 to December 2005 with diagnoses and/or procedures that indicated a current episode of bleeding. The definition was validated by medical record review for a sample of 236 hospitalizations.

Results

We reviewed 186 hospitalizations that had

SUBMITTER: Cunningham A 

PROVIDER: S-EPMC3365595 | biostudies-literature | 2011 Jun

REPOSITORIES: biostudies-literature