Molecular genetic studies of gene identification for osteoporosis: the 2009 update.

ABSTRACT: Osteoporosis is a complex human disease that results in increased susceptibility to fragility fractures. It can be phenotypically characterized using several traits, including bone mineral density, bone size, bone strength, and bone turnover markers. The identification of gene variants that contribute to osteoporosis phenotypes, or responses to therapy, can eventually help individualize the prognosis, treatment, and prevention of fractures and their adverse outcomes. Our previously published reviews have comprehensively summarized the progress of molecular genetic studies of gene identification for osteoporosis and have covered the data available to the end of September 2007. This review represents our continuing efforts to summarize the important and representative findings published betw

SUBMITTER: Xu XH 

PROVIDER: S-EPMC3365849 | biostudies-literature | 2010 Aug

REPOSITORIES: biostudies-literature