Unknown

Dataset Information

0

Total syntheses of graphisin A and sydowinin B.

ABSTRACT: Efficient syntheses of the highly substituted benzophenone graphisin A and the xanthone sydowinin B are described. Key steps involve aryl anion addition to substituted benzaldehyde derivatives, subsequent methyl ester installation, and dehydrative cyclization. Oxidation of graphisin A led to a spirodienone derived from a highly substituted benzoquinone intermediate.

SUBMITTER: Little A 

PROVIDER: S-EPMC3367002 | biostudies-literature | 2012 Jun

REPOSITORIES: biostudies-literature

Json Xml
altmetric image

Publications

Total syntheses of graphisin A and sydowinin B.

Little Andrew A   Porco John A JA  

Organic letters 20120523 11

Efficient syntheses of the highly substituted benzophenone graphisin A and the xanthone sydowinin B are described. Key steps involve aryl anion addition to substituted benzaldehyde derivatives, subsequent methyl ester installation, and dehydrative cyclization. Oxidation of graphisin A led to a spirodienone derived from a highly substituted benzoquinone intermediate. ...[more]

Similar Datasets

Unknown Total syntheses of kealiinines A-C.
| S-EPMC3876472 | biostudies-literature
Unknown Total syntheses of (+)- and (-)-peribysin E.
| S-EPMC2646880 | biostudies-literature
Unknown Total syntheses of strained polycyclic terpenes.
| S-EPMC9017437 | biostudies-literature
Unknown Practical total syntheses of epiquinamide enantiomers.
| S-EPMC2647512 | biostudies-literature
Unknown Total syntheses of (+/-)-platencin and (-)-platencin.
| S-EPMC2783895 | biostudies-literature
Unknown Total and Formal Syntheses of Fostriecin.
| S-EPMC7654735 | biostudies-literature
Unknown Total syntheses and structural revision of alpha- and beta-diversonolic esters and total syntheses of diversonol and blennolide C.
| S-EPMC2790823 | biostudies-literature
Unknown Total syntheses of (+)-tedanolide and (+)-13-deoxytedanolide.
| S-EPMC2645944 | biostudies-literature
Unknown Divergent total syntheses of (-)-aspidospermine and (+)-spegazzinine.
| S-EPMC3337885 | biostudies-literature
Unknown Divergent Total Syntheses of (-)-Pseudocopsinine and (-)-Minovincinine.
| S-EPMC7718306 | biostudies-literature