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The biosynthetic products of Chinese insect medicine, Aspongopus chinensis.


ABSTRACT: A new oxazole (1) was obtained from Chinese insect medicine Aspongopus chinensis, along with three known N-acetyldopamine derivatives (2-4). Their structures were determined on the basis of NMR and ESI-MS analyses. The possible biosynthetic pathways of the isolated compounds are discussed. Cytotoxicities of those compounds against 10 selected cancer cells were measured in vitro.

SUBMITTER: Luo XH 

PROVIDER: S-EPMC3367025 | biostudies-literature | 2012 Jun

REPOSITORIES: biostudies-literature

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The biosynthetic products of Chinese insect medicine, Aspongopus chinensis.

Luo Xiao-Hong XH   Wang Xiao-Zheng XZ   Jiang Hai-Long HL   Yang Jun-Li JL   Crews Phillip P   Valeriote Frederick A FA   Wu Quan-Xiang QX  

Fitoterapia 20120311 4


A new oxazole (1) was obtained from Chinese insect medicine Aspongopus chinensis, along with three known N-acetyldopamine derivatives (2-4). Their structures were determined on the basis of NMR and ESI-MS analyses. The possible biosynthetic pathways of the isolated compounds are discussed. Cytotoxicities of those compounds against 10 selected cancer cells were measured in vitro. ...[more]

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