Location-weighted CTP analysis predicts early motor improvement in stroke: a preliminary study.

ABSTRACT:

Objective

To develop multivariate models for prediction of early motor deficit improvement in acute stroke patients with focal extremity paresis, using admission clinical and imaging data.

Methods

Eighty consecutive patients with motor deficit due to first-ever unilateral stroke underwent CT perfusion (CTP) within 9 hours of symptom onset. Limb paresis was prospectively assessed using admission and discharge NIH Stroke Scale (NIHSS) scoring. CTP scans were coregistered to the MNI-152 brain space and subsegmented to 146 pairs of cortical/subcortical regions based on preset atlases. Stepwise multivariate binary logistic regressions were performed to determine independent clinical and imaging predictors of paresis improvement.

Results

The rates of early motor deficit imp

SUBMITTER: Payabvash S 

PROVIDER: S-EPMC3369521 | biostudies-literature | 2012 Jun

REPOSITORIES: biostudies-literature