Chronic lung disease in adolescents with delayed diagnosis of vertically acquired HIV infection.

ABSTRACT:

Background

Long-term survivors of vertically acquired human immunodeficiency virus (HIV) infection are reaching adolescence in large numbers in Africa and are at high risk of delayed diagnosis and chronic complications of untreated HIV infection. Chronic respiratory symptoms are more common than would be anticipated based on the HIV literature.

Methods

Consecutive adolescents with presumed vertically acquired HIV attending 2 HIV care clinics in Harare, Zimbabwe, were recruited and assessed with clinical history and examination, CD4 count, pulmonary function tests, Doppler echocardiography, and chest radiography (CXR). Those with suspected nontuberculous chronic lung disease (CLD) were scanned using high-resolution computed tomography (HRCT).

Results

Of 116 participant

SUBMITTER: Ferrand RA 

PROVIDER: S-EPMC3369563 | biostudies-literature | 2012 Jul

REPOSITORIES: biostudies-literature