Effect of pre-diabetes on future risk of stroke: meta-analysis.

ABSTRACT:

Objectives

To assess the association between pre-diabetes and risk of stroke, and to evaluate whether this relation varies by diagnostic criteria for pre-diabetes.

Design

Systematic review and meta-analysis of prospective studies.

Data sources

A search of Medline, Embase, and the Cochrane Library (1947 to 16 July 2011) was supplemented by manual searches of bibliographies of key retrieved articles and relevant reviews.

Selection criteria

Prospective cohort studies that reported multivariate adjusted relative risks and corresponding 95% confidence intervals for stroke with respect to baseline pre-diabetes were included.

Data extraction

Two independent reviewers extracted data on pre-diabetes status at baseline, risk estimates of stroke, study quality, and

SUBMITTER: Lee M 

PROVIDER: S-EPMC3370083 | biostudies-literature | 2012 Jun

REPOSITORIES: biostudies-literature