Visceral adiposity is not associated with inflammatory markers in trauma patients.

ABSTRACT:

Background

Excess visceral adiposity induces chronic subclinical inflammation resulting in the metabolic syndrome. Whether excess visceral adiposity impacts posttraumatic inflammatory profiles more is unknown. We hypothesized that obese patients (body mass index >30 kg/m) with higher visceral to subcutaneous adipose tissue distribution would have increased inflammatory outcomes.

Methods

A secondary analysis of a prospective cohort of adult trauma patients requiring >48 hours of intensive care unit care over a 55-month period was analyzed. Body fat distribution was determined by radiologist review of computed tomography scans at L1. Concentric freeform regions were defined manually, and area was calculated. Visceral adiposity was defined as subcutaneous fat area: visceral are

SUBMITTER: Collier B 

PROVIDER: S-EPMC3371365 | biostudies-literature | 2010 Jan

REPOSITORIES: biostudies-literature