Ontology highlight
ABSTRACT:
SUBMITTER: Malik-Kale P
PROVIDER: S-EPMC3374820 | biostudies-literature | 2012
REPOSITORIES: biostudies-literature
Malik-Kale Preeti P Winfree Seth S Steele-Mortimer Olivia O
PloS one 20120613 6
Salmonella enterica serovar Typhimurium invades and proliferates within epithelial cells. Intracellular bacteria replicate within a membrane bound vacuole known as the Salmonella containing vacuole. However, this bacterium can also replicate efficiently in the cytosol of epithelial cells and net intracellular growth is a product of both vacuolar and cytosolic replication. Here we have used semi-quantitative single-cell analyses to investigate the contribution of each of these replicative niches ...[more]