Deoxy Derivatives of L-like 5'-Noraristeromycin.

ABSTRACT: Several base variations of 2'- and 3'-deoxy derivatives of (+)-4'-deoxy-5'-noraristeromycin have been prepared from enantiomerically pure precursors following standard purine nucleoside construction. These carbocyclic nucleosides were evaluated against hepatitis B virus (HBV) and found to be inactive. No cytotoxicity to the cell line was observed.

SUBMITTER: Hinton S 

PROVIDER: S-EPMC3375702 | biostudies-literature | 2012 Apr

REPOSITORIES: biostudies-literature