Concurrent fNIRS and fMRI processing allows independent visualization of the propagation of pressure waves and bulk blood flow in the cerebral vasculature.

ABSTRACT: Blood Oxygen Level Dependent (BOLD) functional magnetic resonance imaging (fMRI) measures changes in blood oxygenation, which is affected by physiological processes, including cardiac pulsation, breathing, and low frequency oscillations (LFO). It is challenging to identify spatial and temporal effects of these processes on the BOLD signal because the low sampling rate of BOLD leads to aliasing of higher frequency physiological signal components. In this study, we used concurrent functional near infrared spectroscopy (fNIRS) and fMRI on 6 subjects during a resting state scan. To reduce aliasing, the BOLD fMRI acquisition was repeatedly performed on a set of sequentially acquired slice stacks to lower the TR to 0.5s while retaining high spatial resolution. Regressor interpolation at progress

SUBMITTER: Tong Y 

PROVIDER: S-EPMC3376221 | biostudies-literature | 2012 Jul

REPOSITORIES: biostudies-literature