Dataset Information
Multidrug-resistant (MDR) Klebsiella pneumoniae clinical isolates: a zone of high heterogeneity (HHZ) as a tool for epidemiological studies.
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ABSTRACT:
SUBMITTER: Ramirez MS
PROVIDER: S-EPMC3377791 | biostudies-literature | 2012 Jul
REPOSITORIES: biostudies-literature
Publications
Multidrug-resistant (MDR) Klebsiella pneumoniae clinical isolates: a zone of high heterogeneity (HHZ) as a tool for epidemiological studies.
Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20120502 7
Comparison of genome-wide, high-resolution restriction maps of Klebsiella pneumoniae clinical isolates, including an NDM-1 producer, and in silico-generated restriction maps of sequenced genomes revealed a highly heterogeneous region we designated the 'high heterogeneity zone' (HHZ). The HHZ consists of several regions, including a 'hot spot' prone to insertions and other rearrangements. The HHZ is a characteristic genomic area that can be used in the identification and tracking of outbreak-caus ...[more]