Bidomain ECG simulations using an augmented monodomain model for the cardiac source.

ABSTRACT: The electrocardiogram (ECG) is an essential clinical tool for the non-invasive assessment of cardiac function. Computational simulations of ECGs using bidomain models are considered the biophysically most detailed approach, but computational costs are significant. Alternatively, pseudo-bidomain formulations can be used, combining a monodomain model with an infrequent bidomain solve to obtain full extracellular potential (φ(e)) distributions and traces. However, previous attempts at such approaches did not see the expected significant decrease in compute time and did not include important effects of bath-loading on activation wavefront morphology (present in full bidomain models), representing a less accurate source term for φ(e) solution. ECG traces can also be derived from computationally

SUBMITTER: Bishop MJ 

PROVIDER: S-EPMC3378475 | biostudies-literature | 2011 Aug

REPOSITORIES: biostudies-literature