Human skin microbiota: high diversity of DNA viruses identified on the human skin by high throughput sequencing.

ABSTRACT: The human skin is a complex ecosystem that hosts a heterogeneous flora. Until recently, the diversity of the cutaneous microbiota was mainly investigated for bacteria through culture based assays subsequently confirmed by molecular techniques. There are now many evidences that viruses represent a significant part of the cutaneous flora as demonstrated by the asymptomatic carriage of beta and gamma-human papillomaviruses on the healthy skin. Furthermore, it has been recently suggested that some representatives of the Polyomavirus genus might share a similar feature. In the present study, the cutaneous virome of the surface of the normal-appearing skin from five healthy individuals and one patient with Merkel cell carcinoma was investigated through a high throughput metagenomic sequencing ap

SUBMITTER: Foulongne V 

PROVIDER: S-EPMC3378559 | biostudies-literature | 2012

REPOSITORIES: biostudies-literature