Factors influencing response to Botulinum toxin type A in patients with idiopathic cervical dystonia: results from an international observational study.

ABSTRACT:

Objectives

Real-life data on response to Botulinum toxin A (BoNT-A) in cervical dystonia (CD) are sparse. An expert group of neurologists was convened with the overall aim of developing a definition of treatment response, which could be applied in a non-interventional study of BoNT-A-treated subjects with CD.

Design

International, multicentre, prospective, observational study of a single injection cycle of BoNT-A as part of normal clinical practice.

Setting

38 centres across Australia, Belgium, Czech Republic, France, Germany, The Netherlands, Portugal, Russia and the UK.

Participants

404 adult subjects with idiopathic CD. Most subjects were women, aged 41-60 years and had previously received BoNT-A.

Outcome measures

Patients were classified as responder

SUBMITTER: Misra VP 

PROVIDER: S-EPMC3378940 | biostudies-literature | 2012

REPOSITORIES: biostudies-literature