Regio- and enantioselective hydroamination of dienes by gold(I)/menthol cooperative catalysis.

ABSTRACT: Alcohol is key: regio- and enantioselective hydroamination of 1,3-dienes has been achieved with the dinuclear catalyst (R)-DTBM-SEGPHOS. The rate and selectivity of the reaction are enhanced by alcohol additives like menthol, which coordinates the cationic gold(I) to generate a Brønsted acid that can participate in catalysis. Mbs=p-methoxybenzenesulfonyl.

SUBMITTER: Kanno O 

PROVIDER: S-EPMC3382038 | biostudies-literature | 2011 Oct

REPOSITORIES: biostudies-literature