Neoadjuvant treatment response as an early response indicator for patients with rectal cancer.

ABSTRACT:

Purpose

Neoadjuvant chemoradiotherapy for rectal cancer is associated with improved local control and may result in complete tumor response. Associations between tumor response and disease control following radical resection should be established before tumor response is used to evaluate treatment strategies. The purpose of this study was to assess and compare oncologic outcomes associated with the degree of pathologic response after chemoradiotherapy.

Patients and methods

All patients with locally advanced (cT3-4 or cN+ by endorectal ultrasonography, computed tomography, or magnetic resonance imaging) rectal carcinoma diagnosed from 1993 to 2008 at our institution and treated with preoperative chemoradiotherapy and radical resection were identified, and their records were r

SUBMITTER: Park IJ 

PROVIDER: S-EPMC3383178 | biostudies-literature | 2012 May

REPOSITORIES: biostudies-literature